Olga Kovbasnjuk has her expertise
in intestinal physiology and pathophysiology, with recent emphasis
on the role of intestinal stem cells in tissue regeneration after pathogen-induced injury.
She has adopted the stem cell derived organoid model and transformed the 3D
structures into Matrigel-free intestinal epithelial layers with access to the
luminal and serosal surfaces, thus providing an advantage in studying gut
luminal commensals, microbial infectious agents and testing strategies for
luminally-administered pharmacologic agents to stimulate tissue regeneration