rin Lauschke is particularly interested
in developing human stem cell-based models for predicting developmental
toxicity. During her Ph.D. studies, she developed the PluriBeat assay, a method
that uses hiPSC to model early embryonic development and to study the potentially
hazardous effects of chemicals on embryonic development. She is also using
techniques such as CRISPR/Cas9 gene-editing to develop better assays as well as
transcriptome analysis to study molecular modes-of-action of toxic chemicals.
Human Stem Cell