Neuroimaging is that the visual perform of brain and system. Through neuroimaging designation of current standing and progression of neurodegenerative, medicine, intracranial unwellness is feasible. Neuroimaging includes varied techniques appreciate PET, MRI, and CT for designation. Biomarker will be substance that is introduced into organisms as an indicator for detective work, screening, diagnosing, observation organ perform. Biomarker indicates whether or not there's any unwellness or healthy state. Use of biomarkers is increasing day by day in medication development. Biomarkers ought to be straightforward to live simply modifiable, value effective for treatment and may be according to gender.