Dr. Ugo Rovigatti obtained his Ph.D. degree in Molecular Biology with Summa cum Laude in 1973 and in1999 the Tenured Professorship. From 1979 to 1990 he worked at ICRF in London, UK; the RockefellerUniversity in New York; the Fox Chase Institute in Philadelphia; St. Jude Children’s Hospital in Memphis, TN; the NCI in Frederick, MD; the Ochsner Foundation- Clinic in New Orleans, LA; the Baylor College of Medicine in Houston, TX. Between 1997 and 1999 he was a sabbatical professor in Switzerland. His PI research work has been funded by grants from UICC, ICRETT, SCL, MIUR, MUST, etc. Dr. Rovigatti’s interests in cancer research progressed from work on oncogenic viruses (SV40/ RSV) to oncogenes/TSGs (MYC/ETS), Immunoglobulin Rearrangements (childhood cALL) and pediatric neuroblastoma. Starting from neuroblastoma and prostate cancer studies, he developed a model (based on virus MFV) for the origin of specific genetic aberrations, which is being tested by NGS technology.