Smart drug delivery is a technique of delivering medicine to a patient in a method that increases the concentration of the medicine in some parts of the body relative to others. This means of delivery is largely founded on nanomedicine, which plans to employ nanoparticle-mediated drug delivery in order to contest the downfalls of conventional drug delivery. These nanoparticles would be loaded with Pharmaceutical medicated drugs and targeted to specific parts of the body where there is solely diseased cancer tissue is present, by avoiding interaction with healthy adjacent tissue. The main aim of a targeted drug delivery systems is to prolong, target and localize to have a protected drug interaction with the diseased cancer tissue. The conventional drug delivery system is the absorption of the drug across a biological membrane through the body, whereas the targeted release system releases the drug in a dosage form into the body. The advantages to the targeted release system are the reduction in the frequency of the dosages taken by the patient, having a more uniform effect of the drug, reduction of drug side-effects, and reduced fluctuation in circulating drug levels. The disadvantage of the system is high cost, which makes productivity more difficult and the reduced ability to adjust the dosages.