Cancers is a cell enlargement caused when cells inside the body start developing in an uncontrolled way. Benign tumors, which don't spread to different parts of the body. Probable signs and symptoms a lump, prolonged cough, unexplained weight loss, abnormal bleeding and a change in bowel movements. Cancer biology includes the application of system's biology methods to cancer research, so as to study the disease as a complex adaptive system with evolving properties at various biological scales. It refers the analysis of how the intracellular networks of normal cells are contributed during carcinogenesis to develop effective prognostic models that can assist clinicians and scientists in the validations of new cancer therapies and drugs development.